ABSTRACT
OBJECTIVE: During the epidemic period of COVID-19, the treatment of breast cancer patients is limited to a great extent. Their psychological changes deserve attention. The purpose of this study was to investigate the psychological health, anxiety and depression of breast cancer patients during COVID-19. Compare them with healthy people in the same period, so as to lay a foundation for psychological intervention of breast cancer before and after the COVID-19 outbreak. METHODS: During 2019-01-10 and 2020-01-13, 128 female breast cancer patients in the First(86 cases) and Second(42 cases) Affiliated Hospitals of the Air Force Military Medical University were selected as the study objects (group A), and 121 social healthy adult women randomly answered by the Internet questionnaire were selected as the control group (group B). SCL-90, SAS and SDS were used to complete the questionnaire survey. RESULTS: The positive results of SCL-90 were as follows: anxiety(21.09%) and depression(17.18%) were the most common in group A;Anxiety(14.88%) and hostility(15.7%) were the most common in group B. Factor score analysis showed that depression(t=2.898, P=0.004), anxiety(t=3. 649, P<0.001) and hostility(t=3.824, P<0.001) in group A were higher than those in group B. The depression and anxiety of group B were higher than that of domestic norm. Further SAS and SDS analysis showed that anxiety(t=11.492, P<0.001) and depression(t=10.871, P<0.001) in group A were significantly higher than those in group B. In each subgroup: The psychological problems of depression(t=2.061, P=0.044), anxiety(t=2.183, P=0.039) and hostility(t=2.028, P=0.048) of patients who were under 45 years were more obvious than those patients who were over 45 years. The psychological problems of depression(t=2.759, P=0.007), anxiety(t=2.348, P=0.018) and fear(t=2.182, P=0.043) of the patients without higher education were more obvious than those of the educated. The psychological problems of depression(t=2.064, P=0.043), anxiety(t=2.581, P=0.017) and fear(t=2.086, P=0.041) of the patients who not received surgical treatment were more obvious than those who received surgical treatment. When it talked about living in a city or a country, it showed that only differences in anxiety(t=2.273, P=0.032). CONCLUSION:S During the period of COVID-19, the anxiety and depression symptoms arise between breast cancer patients. This phenomenon deserves special attention by the society and medical staff.
ABSTRACT
OBJECTIVE: Breast cancer patients are affected by the disease or anti-tumor treatment,resulting in a state of low immunity,so they are one of the susceptible populations of the COVID-19.This paper provided diagnosis and treatment recommendations for breast cancer patients during the epidemic of COVID-19.METHODS: Articles were found in VIP,CNKI,PubMed from January 2014 to January 2020 with "COVID-19,breast cancer,guidelines,delaying,timeliness" as keywords.In all,19 English papers and 12 Chinese papers were searched.Choice criteria:(1)Delayed treatment for breast cancer surgery,chemotherapy,radiation,or endocrine therapy;(2)treatment of COVID-19;(3)Guidelines about breast cancer.According to the criteria,20 papers were analyzed and reviewed.RESULTS: Based on the current domestic epidemic situation,for patients with routine reexamination,the reexamination can be postponed when the condition is stable.For advanced patients in the stage of maintenance treatment,the examination should be simplified appropriately according to the patient's symptoms and tumor load,focusing on the target lesions or organs with obvious symptoms.For patients with endocrine therapy,targeted maintenance therapy,bone-related therapy,chemotherapy and radiotherapy,the treatment regimen should be maintained or adjusted according to the disease stage and treatment stage.For breast cancer patients,the operation can be suspended for a short time.If it is determined to perform the operation,the scope of the operation should be reduced as much as possible and the operation time should be shortened.CONCLUSIONS: During the epidemic of COVID-19,the reasonable diagnosis and treatment of breast cancer patients should follow the guidelines.Scientific protection should be provided for patients and medical staff.